Recombinant RSV Glycoprotein G [His]

Product Overview

A DNA sequence encoding the glycoprotein G extracellular domain (Asn 66-Arg297) of human respiratory syncytial virus A (93% homologous with strain rsb1734) (P27022-1) was expressed, with a C-terminal polyhistidine tag.

Nature

Recombinant

Tag/Conjugate

His

Purity

> 92 % as determined by SDS-PAGE

Preservative

None

Storage

Store it under sterile conditions at -70 °C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Introduction

Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells.

Keywords

Paramyxoviridae; hypothetical protein; G Protein; Respiratory Syncytial Virus G Protein; G protein