RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene shares a high degree of sequence identity with RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex. It is believed that this RANBP2 gene family member arose from a duplication event 3 Mb distal to RANBP2. Alternative splicing has been observed for this locus and two variants are described. Additional splicing is suggested but complete sequence for further transcripts has not been determined. [provided by RefSeq, Jul 2008]
Synonyms
RGPD5; RANBP2-like and GRIP domain containing 5; BS63; RGP5; BS-63; HEL161; RANBP2-like and GRIP domain-containing protein 5/6; ranBP2L1; ranBP2-like 1; ranBP2-like 1/2; ran-binding protein 2-like 1; sperm membrane protein BS-63; epididymis luminal protein 161; ran-binding protein 2-like 1/2; RANBP2-like and GRIP domain-containing protein 5
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