Specificity
Each conjugate comprises antigen covalently bound to horseradish peroxide and is suitable as a tracer in immunoassay development.
Alternative Names
Phenylbutazone; Oxyphenbutazone; Butazolidine; Bute
Format
The conjugate is supplied as a concentrate. Dilute as required and use working strength conjugate immediately after dilution
Storage
2 - 8°C for up to 3 months / -20°C for long term storage
Introduction
Phenylbutazone is the major metabolite of Phenylbutazone, an NSAID commonly used in horses. In humans, Phenylbutazone is very dangerous, as it"s use can cause aplastic anemia.
Citations
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Freeman, LC; Narvaez, DF; et al. Depolarization and decreased surface expression of K+ channels contribute to NSAID-inhibition of intestinal restitution. BIOCHEMICAL PHARMACOLOGY 74:74-85(2007).
Saso, L; Valentini, G; et al. Inhibition of protein denaturation by fatty acids, bile salts and other natural substances: A new hypothesis for the mechanism of action of fish oil in rheumatic diseases. JAPANESE JOURNAL OF PHARMACOLOGY 79:89-99(1999).