Product Overview
Blocking/Immunizing peptide for anti-PTPRT antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
Function
alpha-actinin binding; alpha-catenin binding; beta-catenin binding; cadherin binding; delta-catenin binding; gamma-catenin binding; hydrolase activity; protein binding; protein tyrosine phosphatase activity; receptor activity; thiolester hydrolase activit
Synonyms
PTPRT; protein tyrosine phosphatase, receptor type, T; receptor-type tyrosine-protein phosphatase T; KIAA0283; RPTPrho; R-PTP-T; RPTP-rho; receptor protein tyrosine phosphatase; receptor-type tyrosine-protein phosphatase rho;
Citations
Publication ()
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