Product Overview
Blocking/Immunizing peptide for anti-PSD/TYL antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Function
ARF guanyl-nucleotide exchange factor activity; phospholipid binding; protein binding; signal transducer activity;
Synonyms
PSD; pleckstrin and Sec7 domain containing; TYL; EFA6; PSD1; EFA6A; PH and SEC7 domain-containing protein 1; exchange factor for ARF6; pleckstrin-Sec7 domains-containing; pleckstrin homology and SEC7 domain-containing protein 1;
Citations
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Kosacka, J; Nowicki, M; et al. Adipocyte-derived angiopoietin-1 supports neurite outgrowth and synaptogenesis of sensory neurons. JOURNAL OF NEUROSCIENCE RESEARCH 83:1160-1169(2006).
Vinade, L; Petersen, JD; et al. Activation of calpain may alter the postsynaptic density structure and modulate anchoring of NMDA receptors. SYNAPSE 40:302-309(2001).