Human PRKAG3 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-PRKAG3 antibody

Target

PRKAG3

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle. [provided by RefSeq, Jul 2008]

Function

AMP-activated protein kinase activity; ATP binding; nucleotide binding; protein kinase binding;

Synonyms

PRKAG3; protein kinase, AMP-activated, gamma 3 non-catalytic subunit; 5-AMP-activated protein kinase subunit gamma-3; AMPK gamma3; AMPK gamma-3 chain; AMPK subunit gamma-3; 5-AMP-activated protein kinase, gamma-3 subunit; AMPKG3;