Product Overview
Blocking/Immunizing peptide for anti-PRED6/ABCCC13 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene is a member of the superfamily of genes encoding ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This family member is part of the MRP subfamily, which is involved in multi-drug resistance, but the human locus is now thought to be a pseudogene incapable of encoding a functional ABC protein. Alternative splicing results in multiple transcript variants; however, not all variants have been fully described.
Function
ATP binding; ATPase activity, coupled to transmembrane movement of substances;
Synonyms
ABCC13; ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene; ATP binding cassette, sub family C (CFTR/MRP), member 13; ATP-binding cassette protein C13; C21orf73; PRED6;
Citations
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Yabuuchi, H; Takayanagi, S; et al. ABCC13, an unusual truncated ABC transporter, is highly expressed in fetal human liver. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 299:410-417(2002).
Toyoda, Y; Hagiya, Y; et al. MRP class of human ATP binding cassette (ABC) transporters: historical background and new research directions. XENOBIOTICA 38:833-862(2008).