This product (Catalog No. CABT-BL2968) is a rabbit-derived polyclonal antibody raised against human PPP1R3G. It has been affinity purified by Protein A. PPP1R3G (protein phosphatase 1 regulatory subunit 3G) is an important member of phosphatase 1 inhibitor -3 family, which is mainly expressed in liver and muscle and participates in glycogen synthesis and metabolism, insulin signaling pathway and lipid metabolism. PPP1R3G is the direct target of insulin -AKT signaling pathway. Insulin phosphorylates Ser79 site of PPP1R3G through AKT, which promotes its binding with GS, so that GS is dephosphorylated by PP1, thus enhancing glycogen synthesis. CABT-BL2968 is suitable for use in Western blot (WB) (1:500–1:2,000) application. CABT-BL2968 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
Protein phosphatase 1 regulatory subunit 3G; PPP1R3G
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