This gene encodes a Golgi protein with a PDZ domain. The PDZ domain is globular and proteins which contain them bind other proteins through short motifs near the C-termini. Mice which are deficient in the orthologous protein have globozoospermia and are infertile. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Function
frizzled binding; ion channel binding; protein C-terminus binding; protein binding; protein homodimerization activity; small GTPase regulator activity;
Synonyms
GOPC; golgi-associated PDZ and coiled-coil motif containing; CAL; FIG; PIST; GOPC1; dJ94G16.2; Golgi-associated PDZ and coiled-coil motif-containing protein; dJ94G16.2 PIST; fused in glioblastoma; CFTR-associated ligand; PDZ protein interacting specifically with TC10; Golgi associated PDZ and coiled-coil motif containing protein; golgi-associated PDZ and coiled-coil motif containing protein; PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10;
Citations
Publication ()
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