Anti-PEX26 (aa 217-228) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide: C-QKPNLEGSVSHK, corresponding to internal sequence amino acids 217-228 of Human PEX26.

Conjugate

Application Notes

WB: 0.5-1.5μg/ml

Alternative Names

PEX26; peroxisomal biogenesis factor 26; peroxisome biogenesis factor 26; peroxisome assembly protein 26; FLJ20695; AI85321; 4632428M11Rik; FLJ20695; OTTMUSP00000033411; OTTMUSP00000033413; Peroxin 26; Peroxisome assembly protein 26; Peroxisome biogenesis disorder, complementation group 8; Peroxisome biogenesis disorder, complementation group A; Peroxisome biogenesis factor 26; PEX 26; Pex26pM1T; peroxin-26; peroxisome biogenesis disorder, complementation group 8; peroxisome biogenesis disorder, complementation group A; PEX26M1T; Pex26pM1T;

Entrez Gene ID

UniProt ID

Antigen Description

This gene belongs to the peroxin-26 gene family. It is probably required for protein import into peroxisomes. It anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Defects in this gene are the cause of peroxisome biogenesis disorder complementation group 8 (PBD-CG8). PBD refers to a group of peroxisomal disorders arising from a failure of protein import into the peroxisomal membrane or matrix. The PBD group is comprised of four disorders: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). Alternatively spliced transcript variants have been identified for this gene.

Pathway

Peroxisome, organism-specific biosystem; Peroxisome, conserved biosystem;