Human PELP1 peptide

Specificity

Isoform 2 is expressed in breast cancer cell lines. Isoform 1 is widely expressed.

Nature

Synthetic

Tag/Conjugate

Unconjugated

Alternative Names

The Glu-rich region mediates histones interaction.The Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are required for the association with nuclear receptor ESR1.

Format

Liquid

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Entrez Gene ID

Antigen Description

This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. This gene may be involved in the progression of several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Function

poly(A) RNA binding; protein binding;

Synonyms

PELP1; proline, glutamate and leucine rich protein 1; MNAR; P160; proline-, glutamic acid- and leucine-rich protein 1; transcription factor HMX3; proline and glutamic acid rich nuclear protein; modulator of non-genomic activity of estrogen receptor;