Anti-PDLIM3 (full length) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Full length human protein (AAH27870, 1 aa ~ 317 aa).

Conjugate

Application Notes

WB: 1:500-1:1000

Alternative Names

PDLIM3; PDZ and LIM domain 3; PDZ and LIM domain protein 3; ALP; Actinin associated LIM protein; Actinin-associated LIM protein; Alpha actinin 2 associated LIM protein; Alpha-actinin-2-associated LIM protein; DKFZp686L0362; Enigma homolog; PDLI3_HUMAN; PDLIM 3; PDLIM3; PDZ and LIM domain 3; PDZ and LIM domain protein 3; enigma homolog; actinin-associated LIM protein; alpha-actinin-2-associated LIM protein;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. This gene is found near a region of chromosome 4 that has been implicated in facioscapulohumeral muscular dystrophy, but this gene does not appear to be involved in the disease. Two transcript variants encoding different isoforms have been found for this gene.