This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12. [provided by RefSeq, Dec 2010]
Function
DNA binding; metal ion binding; zinc ion binding;
Synonyms
PDCD2; programmed cell death 2; programmed cell death protein 2; RP8; ZMYND7; zinc finger protein Rp-8; zinc finger MYND domain-containing protein 7; MGC12347;
Citations
Publication ()
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