Human PCK1 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-PCK1/PEPCKC (internal region) antibody

Target

PCK1 / PEPCKC (internal region)

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. [provided by RefSeq, Jul 2008]

Function

GDP binding; GTP binding; carboxylic acid binding; lyase activity; magnesium ion binding; manganese ion binding; phosphoenolpyruvate carboxykinase (GTP) activity; purine nucleotide binding;

Synonyms

PCK1; phosphoenolpyruvate carboxykinase 1 (soluble); phosphoenolpyruvate carboxykinase, cytosolic [GTP]; PEPCK C; PEP carboxykinase; phosphopyruvate carboxylase; phosphoenolpyruvate carboxylase; phosphoenolpyruvate carboxykinase, cytosolic; PEPCK1; PEPCKC; PEPCK-C; MGC22652;