Rabbit Anti-Human OTUD3 (a.a. 192-398) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

Recombinant human OTUD3 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 192-398 aa of NM_015207

Conjugate

Application Notes

WB: 1:1000-1:4000
IHC: 1:50-1:500

General Notes

This product (Catalog No. CABT-BL2841) is a rabbit-derived polyclonal antibody raised against human OTUD3, targeting the amino acid region 192–398 of the protein. This antibody exhibits cross-reactivity with Human OTUD3 from mouse. It has been affinity purified by Protein A. OTUD3 is a kind of deubiquitinating enzyme that hydrolyzes 'Lys-6'- and 'Lys-11'-linked polyubiquitin. It's an important regulator of energy metabolism. Glucose and fatty acids trigger its nuclear translocation by CBP-dependent acetylation. In the nucleus, deubiquitinates and stabilizes the nuclear receptor PPARD regulating the expression of various genes involved in glucose and lipid metabolism and oxidative phosphorylation. The calculated MW of OTUD3 is 45 kDa, 29622-1-AP can detect the band around 43 kDa.
CABT-BL2841 is suitable for use in Western blot (WB) (1:1,000–1:4,000), IHC (1:50–1:500) applications.
CABT-BL2841 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

DUBA4; KIAA0459; OTU domain containing 3; RP11 460G22.1

Entrez Gene ID

UniProt ID