This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. This gene has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]
Function
lipid binding; oxysterol binding;
Synonyms
OSBPL5; oxysterol binding protein-like 5; oxysterol-binding protein-related protein 5; KIAA1534; ORP5; ORP-5; OSBP-related protein 5; oxysterol-binding protein homolog 1; oxysterol-binding protein homologue 1; OBPH1; FLJ42929;
Citations
Publication ()
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