This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. The encoded protein is involved in the regulation of cell adhesion and organization of the actin cytoskeleton. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Function
lipid binding;
Synonyms
OSBPL3; oxysterol binding protein-like 3; OSBP3; oxysterol-binding protein-related protein 3; KIAA0704; ORP 3; ORP3; OSBP-related protein 3; oxysterol-binding protein 3; ORP-3; MGC21526; DKFZp667P1518;
Citations
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