NDP blocking peptide (CDBP5841)

Nature
Synthetic
Immunogen
18 amino acids near the amino terminus of human Norrin.
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Procedure
None
Format
Liquid
Concentration
200 μg/mL
Size
0.05mg
Preservative
None
Storage
-20°C
UniProt ID
Antigen Description
This gene encodes a secreted protein with a cystein-knot motif that activates the Wnt/beta-catenin pathway. The protein forms disulfide-linked oligomers in the extracellular matrix. Mutations in this gene result in Norrie disease and X-linked exudative vitreoretinopathy. [provided by RefSeq, Feb 2009]
Function
cytokine activity; frizzled binding; growth factor activity; protein binding; protein homodimerization activity
Synonyms
NDP; Norrie disease (pseudoglioma); ND; EVR2; FEVR; norrin; norrie disease protein; X-linked exudative vitreoretinopathy 2 protein

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