Specificity
Each conjugate comprises antigen covalently bound to horseradish peroxide and is suitable as a tracer in immunoassay development.
Alternative Names
Normeperidine; Norpethidine; Pethidine Intermediate B
Format
The conjugate is supplied as a concentrate. Dilute as required and use working strength conjugate immediately after dilution
Storage
2 - 8°C for up to 3 months / -20°C for long term storage
Introduction
Norpethidine is a controlled drug because of its potential uses in manufacturing both pethidine itself and a range of N-substituted derivatives, but it has little opioid activity in its own right. Instead, norpethidine acts as a stimulant and causes convulsions.
Citations
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Ratcliffe, P; Benchikh, EO; et al. DEVELOPMENT OF A MONOCLONAL ANTIBODY FOR THE DETECTION OF MEPERIDINE AND ITS METABOLITE NORMEPERIDINE. CLINICAL CHEMISTRY AND LABORATORY MEDICINE 49:S797-S797(2011).
Ramirez, J; Innocenti, F; et al. CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes. DRUG METABOLISM AND DISPOSITION 32:930-936(2004).