Product Overview
Nordiazepam, HRP conjugate
Storage
2-8°C short term, -20°C long term
Introduction
Nordazepam (marketed under brand names Nordaz, Stilny, Madar, Vegesan, and Calmday), also known as desoxydemoxepam, nordiazepam and desmethyldiazepam, is a 1,4-benzodiazepine derivative. Like other benzodiazepine derivatives, it has anticonvulsant, anxiolytic, muscle relaxant and sedative properties. However, it is used primarily in the treatment of anxiety. It is an active metabolite of diazepam, chlordiazepoxide, clorazepate, prazepam, pinazepam, and medazepam.
Antigen Description
Nordiazepam is the active metabolite of clorazepate (decarboxylation) and diazepam. Common side effects of nordazepam include somnolence, which is more common in elderly patients and/or people on high dose regimens. Hypotonia, which is much less common, is also associated with high doses and/or old age.
Citations
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JAUREGUI, HO; NG, SF; et al. XENOBIOTIC INDUCTION OF P-450 PB-4 (IIB1) AND P-450C (IA1) AND ASSOCIATED MONOOXYGENASE ACTIVITIES IN PRIMARY CULTURES OF ADULT-RAT HEPATOCYTES. XENOBIOTICA 21:1091-1106(1991).
Yue, N; Wu, LH; et al. Multi-residue detection of benzodiazepines by ELISA based on class selective antibodies. FOOD AND AGRICULTURAL IMMUNOLOGY 20:281-293(2009).