Product Overview
Blocking/Immunizing peptide for anti-Neurexin 3/NRXN3 antibody
Target
Neurexin 3 / NRXN3
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder. [provided by RefSeq, Dec 2012]
Function
metal ion binding; receptor activity;
Synonyms
NRXN3; neurexin 3; C14orf60, chromosome 14 open reading frame 60; neurexin-3-beta; KIAA0743; neurexin III; neurexin III-beta; neurexin III-alpha; C14orf60; MGC176711;
Citations
Publication ()
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