Human PVRL2 peptide

Specificity

Ubiquitous.

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

Belongs to the nectin family.Contains 2 Ig-like C2-type (immunoglobulin-like) domains.Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Purity

70 - 90% by HPLC.

Format

Liquid

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Entrez Gene ID

Antigen Description

This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Function

cell adhesion molecule binding; coreceptor activity; identical protein binding; protein binding; protein homodimerization activity; protein homodimerization activity; virus receptor activity;

Synonyms

PVRL2; poliovirus receptor-related 2 (herpesvirus entry mediator B); HVEB; PRR2; CD112; PVRR2; poliovirus receptor-related protein 2; nectin-2; poliovirus receptor-like 2; herpesvirus entry protein B;