This gene encodes a member of the basic helix-loop-helix and PAS domain-containing family of transcription factors. The encoded protein is localized to the nucleus and may regulate genes involved in neurogenesis. Chromosomal abnormalities that affect the coding potential of this gene are associated with schizophrenia and mental retardation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Function
DNA binding; signal transducer activity;
Synonyms
NPAS3; neuronal PAS domain protein 3; neuronal PAS domain-containing protein 3; bHLHe12; MOP6; PASD6; neuronal PAS3; member of PAS protein 6; PAS domain-containing protein 6; basic-helix-loop-helix-PAS protein MOP6; class E basic helix-loop-helix protein 12; FLJ10003; FLJ11138; FLJ11605;
Citations
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