This gene encodes a member of a family of proteins that function as negative regulators of Wnt receptor signaling through interaction with Dishevelled family members. The encoded protein participates in the delivery of transforming growth factor alpha-containing vesicles to the cell membrane. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
Function
calcium ion binding; protein binding; ubiquitin protein ligase binding;
Synonyms
NKD2; naked cuticle homolog 2 (Drosophila); protein naked cuticle homolog 2; Dvl binding protein NKD2; naked cuticle 2; Naked2; hNkd2; naked-2; naked cuticle-2; Dvl-binding protein NKD2;
Citations
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