Synthetic Human NIPBL blocking peptide for Apuri, BL, ELISA
Blocking/Immunizing peptide for anti-NIPBL (aa922-935) antibody
Human, Mouse, Cow, Dog, Rat
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Shipped at ambient temperature, store at -20°C.
This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
chromo shadow domain binding; histone deacetylase binding; protein C-terminus binding; protein N-terminus binding; protein binding;
NIPBL; Nipped-B homolog (Drosophila); nipped-B-like protein; DKFZp434L1319; FLJ11203; FLJ12597; FLJ13354; FLJ13648; IDN3; Scc2; sister chromatid cohesion 2 homolog (yeast); delangin; SCC2 homolog; sister chromatid cohesion 2 homolog; CDLS; CDLS1; IDN3-B; FLJ44854;