Human NAIP blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-NAIP antibody

Target

NAIP

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function

ATP binding; metal ion binding; nucleoside-triphosphatase activity; nucleotide binding; protein binding;

Synonyms

NAIP; NLR family, apoptosis inhibitory protein; baculoviral IAP repeat containing 1 , BIRC1; baculoviral IAP repeat-containing protein 1; NLR family; BIR domain containing 1; NLRB1; nucleotide binding oligomerization domain; leucine rich repeat and BIR domain containing 1; neuronal apoptosis inhibitory protein; psi neuronal apoptosis inhibitory protein; nucleotide-binding oligomerization domain, leucine rich repeat and BIR domain containing 1; BIRC1; psiNAIP; FLJ18088; FLJ42520; FLJ58811;