Specificity
Mostly in developing nervous system. Expressed in neural progenitors and oligodendrocyte lineage cells. More highly expressed in oligodendrocyte progenitors than in differentiated oligodendrocytes.
Tag/Conjugate
Unconjugated
SequenceSimilarities
Contains 7 C2HC-type zinc fingers.
Alternative Names
Contains 7 zinc fingers of the C2HC class arranged in two widely separated clusters. These two domains of DNA binding can function independently and recognize the same DNA sequence.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Antigen Description
The protein encoded by this gene is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system. [provided by RefSeq, Jul 2008]
Function
enhancer sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; zinc ion binding;
Synonyms
MYT1; myelin transcription factor 1; MTF1; MYTI; NZF2; PLPB1; ZC2HC4A; C20orf36; myelin transcription factor I; proteolipid protein binding protein; proteolipid protein-binding protein; neural zinc finger transcription factor 2;
Citations
Publication ()
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COA
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