Human MSX2 peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

Belongs to the Msh homeobox family.Contains 1 homeobox DNA-binding domain.

Purity

70 - 90% by HPLC.

Format

Liquid

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Entrez Gene ID

Antigen Description

This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. [provided by RefSeq, Jul 2008]

Function

RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; protein binding; sequence-specific DNA binding; transcription cofac

Synonyms

MSX2; msh homeobox 2; FPP; MSH; PFM; CRS2; HOX8; PFM1; homeobox protein MSX-2; msh homeo box 2; homeobox protein Hox-8; msh homeobox homolog 2;