Anti-WDR36 monoclonal antibody, clone 2E7

Antibody Isotype

IgG2a

Clone

2E7

Species Reactivity

Human

Immunogen

WDR36 (NP_644810, 853 a.a. ~ 952 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Alternative Names

WD repeat domain 36; DKFZp686I1650; TA-WDRP; OTTHUMP00000158997; UTP21; OTTHUMP00000223490; T-cell activation WD repeat-containing protein; OTTHUMP00000223962; GLC1G; OTTHUMP00000223963; TAWDRP; T-cell activation WD repeat protein; glaucoma 1, open angle,

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG).
Mouse monoclonal antibody raised against a partial recombinant WDR36.

Pathway

Ribosome biogenesis in eukaryotes, organism-specific biosystem; Ribosome biogenesis in eukaryotes, conserved biosystem.