Anti-TRIM31 monoclonal antibody (CABT-19151MH)

Mouse anti-Human TRIM31 monoclonal antibody for IF, sELISA, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
3H22
Species Reactivity
Human
Immunogen
TRIM31 (NP_008959, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
tripartite motif containing 31; tripartite motif-containing 31; C6orf13; RNF; ring finger protein; HCGI
Entrez Gene ID
UniProt ID

Product Background


Gene summary
TRIM31 (Tripartite Motif Containing 31) is a Protein Coding gene. Among its related pathways are Immune System and Interferon gamma signaling. GO annotations related to this gene include ligase activity. An important paralog of this gene is TRIM58. This gene encodes a protein that functions as an E3 ubiquitin-protein ligase. This gene shows altered expression in certain tumors and may be a negative regulator of cell growth. Alternative splicing results in multiple transcript variants.
Antigen Description
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to both the cytoplasm and the nucleus. Its function has not been identified.
Mouse monoclonal antibody raised against a partial recombinant TRIM31. Regulator of Src-induced anchorage independent cell growth (By similarity). May have E3 ubiquitin-protein ligase activity. Tripartite motif-containing protein 31 is a protein that in humans is encoded by the TRIM31 gene. 0The function about TRIM31 antigen include ligase activity; metal ion binding; zinc ion binding.

Citations


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References


Burbelo, PD; Ching, KH; et al. Extraordinary antigenicity of the human Ro52 autoantigen. AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH 2:145-155(2010).

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