Specifications
Immunogen
PROCR (AAH14451, 1 a.a. ~ 239 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
Alternative Names
protein C receptor, endothelial; CCCA; EPCR; MGC23024; CCD41; OTTHUMP00000030729; CD201; bA42O4.2; Activated protein C receptor; cell cycle, centrosome-associated protein; Endothelial cell protein C receptor; centrocyclin; APC receptor; endothelial protei
Product Background
Antigen Description
The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy.
Mouse monoclonal antibody raised against a full length recombinant PROCR.
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Ariano, P; Dalmazzo, S; et al. TRPC channels are involved in calcium-dependent migration and proliferation in immortalized GnRH neurons. CELL CALCIUM 49:387-394(2011).
Cocco, E; Varughese, J; et al. Expression of Tissue factor in Adenocarcinoma and Squamous Cell Carcinoma of the Uterine Cervix: Implications for immunotherapy with hI-con1, a factor VII-IgGF(c) chimeric protein targeting tissue factor. BMC CANCER 11:-(2011).