Specifications
Immunogen
MUC5B (XP_039877, 4186 a.a. ~ 4296 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
Alternative Names
MG1; MUC5; MUC9; MUC-5B; mucin-5B; OTTHUMP00000233052; cervical mucin MUC5B; sublingual gland mucin; mucin-5 subtype B, tracheobronchial; mucin 5, subtype B, tracheobronchial; high molecular weight salivary mucin MG1
Product Background
Antigen Description
This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases.
Mouse monoclonal antibody raised against a partial recombinant MUC5B.
Pathway
Salivary secretion, organism-specific biosystem; Salivary secretion, conserved biosystem
Citations
Publication ()
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