Anti-INPP4B monoclonal antibody, clone 4G3

Antibody Isotype

IgG2b

Clone

4G3

Species Reactivity

Human

Immunogen

INPP4B (AAH05273, 1 a.a. ~ 54 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Alternative Names

inositol polyphosphate-4-phosphatase, type II, 105kDa; OTTHUMP00000220068; Inositol polyphosphate 4-phosphatase type II; OTTHUMP00000220069; EC 3.1.3.66; OTTHUMP00000220070; inositol polyphosphate-4-phosphatase, type II, 105kD; OTTHUMP00000220071; MGC1320

Entrez Gene ID

UniProt ID

Antigen Description

INPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme.
Mouse monoclonal antibody raised against a full-length recombinant INPP4B.

Pathway

3-phosphoinositide degradation, conserved biosystem; Inositol phosphate metabolism, organism-specific biosystem; Inositol phosphate metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Phosphatidylinositol signaling system, organism-specific biosystem; Phosphatidylinositol signaling system, conserved biosystem.