Specifications
Immunogen
A synthetic peptide corresponding to residues surrounding amino acids 21 of human CTSL2.
Applications
Application Notes
WB (1-4 μg/mL); Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (20-30 μg/mL) & The optimal working dilution should be determined by the end user.
Target
Alternative Names
cathepsin L2; CATL2; CTSV; MGC125957; CTSU; cathepsin L2, preproprotein; Cathepsin U; EC 3.4.22.43; Cathepsin V; EC 3.4.22; OTTHUMP00000021738
Product Background
Antigen Description
The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified.
Mouse monoclonal antibody raised against synthetic peptide of CTSL2.
Pathway
Endochondral Ossification, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem.
Citations
Publication ()
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COA
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