Tag/Conjugate
Unconjugated
Alternative Names
The leucine-zipper domain is involved in the interaction with LRPICD.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Antigen Description
The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns. [provided by RefSeq, Jul 2008]
Function
protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor binding;
Synonyms
MAFB; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B; KRML; MCTO; transcription factor MafB; Kreisler maf-related leucine zipper homolog; MAFB/Kreisler basic region/leucine zipper transcription factor;
Citations
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Xiu, FM; Stanojcic, M; et al. Norepinephrine Inhibits Macrophage Migration by Decreasing CCR2 Expression. PLOS ONE 8:-(2013).
Pise-Masison, CA; Radonovich, M; et al. Gene expression profiling of ATL patients: compilation of disease-related genes and evidence for TCF4 involvement in BIRC5 gene expression and cell viability. BLOOD 113:4016-4026(2009).