Rabbit Anti-Human MYO3B (C-terminal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

A synthesized peptide derived from human MYO3B, corresponding to a region within C-terminal amino acids.

Conjugate

Application Notes

IF/ICC 1:100-1:500
WB 1:1000-3000
IHC 1:50-1:200

General Notes

This product (Catalog No. CABT-BL2556) is a rabbit-derived polyclonal antibody raised against human MYO3B. This antibody exhibits cross-reactivity with MYO3B from mouse. It has been affinity purified by Protein A. Probable actin-based motor with a protein kinase activity. Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern. Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments.
CABT-BL2556 is suitable for use in IF/ICC 1 (100-1:500), WB 1 (1000-3000), IHC 1 (50-1:200) applications.
CABT-BL2556 is supplied as a liquid formulation in Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Entrez Gene ID

UniProt ID