Human ABCC11 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-MRP8/ABCC11 antibody

Target

MRP8 / ABCC11

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Gene ID

85320

UniProt ID

Q96J66

Antigen Description

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene.

Function

ATP binding; ATPase activity; ATPase activity, coupled to transmembrane movement of substances; nucleotide binding;

Synonyms

ABCC11; ATP-binding cassette, sub-family C (CFTR/MRP), member 11; ATP-binding cassette sub-family C member 11; MRP8; multi-resistance protein 8; ATP-binding cassette protein C11; ATP-binding cassette transporter MRP8; multidrug resistance-associated protein 8; ATP-binding cassette transporter sub-family C member 11; WW; EWWD;