General Notes
This product (Catalog No. CABT-BL5185) is a rabbit-derived polyclonal antibody raised against human MPP7, targeting the amino acid region 269–576 of the protein. This antibody exhibits cross-reactivity with Human MPP7 from mouse and rat. It has been affinity purified by Protein A. Membrane-associated guanylate kinases (MAGUKs) are important adaptor proteins involved in the assembly of protein;complexes at sites of cell-cell contact. They are found in synapses, adherens junctions, and tight junctions. All;MAGUKs contain at least 1 PDZ domain, an SH3 domain, and a GUK domain, and many contain 1 or 2 L27 domains, which are;involved in multimerization of MAGUKs. MPP7 belongs to the p55 stardust subfamily of MAGUKs, which is named for a;Drosophila gene required for establishment of cell polarity in the developing fly embryo (Bohl et al., 2007 (PubMed;17237226)).
CABT-BL5185 is suitable for use in Western blot (WB) (1:1,000–1:8,000), IP (0.5-4.0 μg for 1.0-3.0 mg of total protein lysate), IHC (1:20–1:200) applications.
CABT-BL5185 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.