Rabbit Anti-Human MPDZ (a.a. 751-1100) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant human MUPP1 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 751-1100 aa of BC140793

Conjugate

Application Notes

WB: 1:500-1:2000

General Notes

This product (Catalog No. CABT-BL2498) is a rabbit-derived polyclonal antibody raised against human MPDZ, targeting the amino acid region 751–1100 of the protein. It has been affinity purified by Protein A. The PDZ domain is a protein motif that mediates protein-protein interactions. MUPP1(multi-PDZ domain protein-1) has 13 PDZ domains, each containing the structural characteristics of a prototypic PDZ motif, but lacks a catalytic domain. MUPP1 belongs to the PDZ domain protein family and is a structural homologant of PATJ (PALS1-associated tight-linking protein) (PMID: 23880463). MUPP1 is a scaffold protein and plays an important role in cytoskeletal organization, cell polarity, and cell proliferation(PMID: 25662616). Mutations in MUPP1 are associated with congenital hydrocephalus(PMID: 23240096).
CABT-BL2498 is suitable for use in Western blot (WB) (1:500–1:2,000) application.
CABT-BL2498 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

MPDZ; MUPP1

Entrez Gene ID

UniProt ID