Synthetic Human MLH3 blocking peptide for Apuri, BL, ELISA
Blocking/Immunizing peptide for anti-MLH3 antibody
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Shipped at ambient temperature, store at -20°C.
This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
ATP binding; ATPase activity; centromeric DNA binding; chromatin binding; mismatched DNA binding; mismatched DNA binding; protein binding; satellite DNA binding;
MLH3; mutL homolog 3 (E. coli); mutL (E. coli) homolog 3; DNA mismatch repair protein Mlh3; mutL protein homolog 3; HNPCC7; MGC138372;