Specificity
Expressed in liver, skeletal muscle, heart, pancreas, and placenta. Not detected in brain, lung or kidney. Expressed in several lung cancer tissues, but is barely detected in the adjacent non-cancerous tissues. Also highly expressed in several esophageal
Tag/Conjugate
Unconjugated
SequenceSimilarities
Belongs to the MINA53/NO66 family.Contains 1 JmjC domain.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Antigen Description
MINA is a c-Myc (MYC; MIM 190080) target gene that may play a role in cell proliferation or regulation of cell growth. (Tsuneoka et al., 2002 [PubMed 12091391]; Zhang et al., 2005 [PubMed 15897898]).[supplied by OMIM, May 2008]
Function
RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; dioxygenase activity; metal ion binding;
Synonyms
MINA; MYC induced nuclear antigen; ROX; MDIG; NO52; MINA53; bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA; nucleolar protein 52; ribosomal oxygenase MINA; histone lysine demethylase MINA; mineral dust induced gene protein; mineral dust-induced gene protein; myc-induced nuclear antigen, 53 kDa; 60S ribosomal protein L27a histidine hydroxylase;
Citations
Publication ()
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COA
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