Species Reactivity: Mouse, Human, Rat, Pig, Cow, Rabbit, Sheep
Summary
Specifications
Antibody Isotype
IgG
Species Reactivity
Mouse; Human; Rat; Pig; Cow; Rabbit; Sheep
Immunogen
KLH conjugated synthetic peptide derived from human MFSD8: 301-400/518
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 1:100-500 IHC-F: 1:100-500 IF: 1:100-500
General Notes
This product (Catalog No. CABT-BL2386) is a rabbit-derived IgG polyclonal antibody raised against human MFSD8, targeting the amino acid region 301–400 of the protein. This antibody exhibits cross-reactivity with MFSD8 from mouse, rat, pig, cow, rabbit, and sheep. It has been affinity purified by protein A. This gene encodes a ubiquitous integral membrane protein that contains a transporter domain and a major facilitator superfamily (MFS) domain. Other members of the major facilitator superfamily transport small solutes through chemiosmotic ion gradients. The substrate transported by this protein is unknown. The protein likely localizes to lysosomal membranes. Mutations in this gene are correlated with a variant form of late infantile-onset neuronal ceroid lipofuscinoses (vLINCL). CABT-BL2386 is suitable for use in IHC-P (1:100–1:500), IHC-F (1:100–1:500), IF (immunofluorescence) (1:100–1:500) applications. CABT-BL2386 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
Ceroid-lipofuscinosis neuronal protein 7; CLN7; Major facilitator superfamily domain-containing protein 8; MFSD8; MFSD8_HUMAN
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