Specificity
Normal mammary epithelial cells.
Tag/Conjugate
Unconjugated
SequenceSimilarities
Belongs to the serpin family. Ov-serpin subfamily.
Purity
> 95 % by SDS-PAGE.
Buffer
Preservative: None Constituents: 0.001% Tween 20, 30mM HEPES, 2mM EDTA, 150mM Sodium chloride, pH 6.75
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. Preservative: None Constituents: 0.001% Tween 20, 30mM HEPES, 2mM EDTA, 150mM Sodium chloride, pH 6.75
Antigen Description
Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Function
protein binding; serine-type endopeptidase inhibitor activity;
Synonyms
SERPINB5; serpin peptidase inhibitor, clade B (ovalbumin), member 5; PI5; maspin; serpin B5; PI-5; peptidase inhibitor 5; protease inhibitor 5 (maspin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5;
Citations
Publication ()
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COA
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