This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding the same protein have been identified for this gene.
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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GIL, ML; VITA, N; et al. A MEMBER OF THE TETRA SPANS TRANSMEMBRANE PROTEIN SUPERFAMILY IS RECOGNIZED BY A MONOCLONAL-ANTIBODY RAISED AGAINST AN HLA CLASS-I-DEFICIENT, LYMPHOKINE-ACTIVATED KILLER-SUSCEPTIBLE, LYMPHOCYTE-B LINE - CLONING AND PRELIMINARY FUNCTIONAL-STUDIES. JOURNAL OF IMMUNOLOGY 148:2826-2833(1992).
Nakagawa, K; Noguchi, Y; et al. XAGE-1 expression in non-small cell lung cancer and antibody response in patients. CLINICAL CANCER RESEARCH 11:5496-5503(2005).
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