Human MACC1 blocking peptide (CDBP1801)

Synthetic Human MACC1 blocking peptide for BL

Product Overview
Blocking peptide for anti-MACC1 antibody
Target
MACC1
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not suitable for human or animal consumption.
Procedure
None
Format
Liquid
Concentration
200 μg/ml
Size
50 μg
Buffer
PBS containing 0.02% sodium azide
Preservative
0.02% Sodium Azide
Storage
Store at -20℃, stable for one year.
UniProt ID
Antigen Description
MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009]
Function
growth factor activity;
Synonyms
MACC1; metastasis associated in colon cancer 1; metastasis-associated in colon cancer protein 1; 7A5; SH3BP4L; putative binding protein 7a5; SH3 domain-containing protein 7a5;

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References


Huang, WH; Chang, MC; et al. Mesenchymal stem cells promote growth and angiogenesis of tumors in mice. ONCOGENE 32:4343-4354(2013).
Perez, RO; Bresciani, BH; et al. Mucinous colorectal adenocarcinoma: influence of mucin expression (Muc1, 2 and 5) on clinico-pathological features and prognosis. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE 23:757-765(2008).

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