Human LIG1 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-LIG1/DNA ligase I antibody

Target

LIG1 / DNA ligase I

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Function

ATP binding; DNA binding; DNA ligase (ATP) activity; DNA ligase activity; ligase activity; metal ion binding; nucleotide binding;

Synonyms

LIG1; ligase I, DNA, ATP-dependent; DNA ligase 1; polydeoxyribonucleotide synthase [ATP] 1; MGC117397; MGC130025;