Human LARGE blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-LARGE (N-terminus) antibody

Target

LARGE (N-terminus)

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

This gene, which is one of the largest in the human genome, encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. Mutations in this gene cause MDC1D, a novel form of congenital muscular dystrophy with severe mental retardation and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]

Function

acetylglucosaminyltransferase activity; transferase activity, transferring glycosyl groups;

Synonyms

LARGE; like-glycosyltransferase; MDC1D; MDDGA6; MDDGB6; glycosyltransferase-like protein LARGE1; like-acetylglucosaminyltransferase; acetylglucosaminyltransferase-like 1A; acetylglucosaminyltransferase-like protein;