Product Overview
Blocking/Immunizing peptide for anti-Klk6/neurosin (mouse) antibody
Target
Klk6 / neurosin (mouse)
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Function
hydrolase activity; peptidase activity; serine-type endopeptidase activity; serine-type peptidase activity;
Synonyms
KLK6; kallikrein related-peptidase 6; protease M; kallikrein 6; kallikrein 29; protease, serine, 9; protease, serine, 18; brain serine protease; myofibril-bound protease; myelencephalon-specific protease; BSP; MSP; Bssp; Klk29; Prss9; Prss18; AI849898; neurosin;
Citations
Publication ()
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