Human KCNE2 peptide

Specificity

Highly expressed in brain, heart, skeletal muscle, pancreas, placenta, kidney, colon and thymus. A small but significant expression is found in liver, ovary, testis, prostate, small intestine and leukocytes. Very low expression, nearly undetectable, in lu

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

Belongs to the potassium channel KCNE family.

Purity

70 - 90% by HPLC.

Format

Liquid

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Entrez Gene ID

Antigen Description

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a small integral membrane subunit that assembles with the KCNH2 gene product, a pore-forming protein, to alter its function. This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia. [provided by RefSeq, Jul 2008]

Function

contributes_to delayed rectifier potassium channel activity; contributes_to inward rectifier potassium channel activity; ion channel binding; potassium channel regulator activity; protein homodimerization activity; voltage-gated potassium channel activity

Synonyms

KCNE2; potassium voltage-gated channel, Isk-related family, member 2; LQT5; LQT6; ATFB4; MIRP1; potassium voltage-gated channel subfamily E member 2; minK-related peptide 1; minK-related peptide-1; potassium channel subunit, MiRP1; potassium channel subunit beta MiRP1; voltage-gated K+ channel subunit MIRP1; minimum potassium ion channel-related peptide 1; cardiac voltage-gated potassium channel accessory subunit 2;