Product Overview
Blocking/Immunizing peptide for anti-KALRN antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Function
ATP binding; Rho guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; metal ion binding; nucleotide binding; protein serine/threonine kinase activity;
Synonyms
KALRN; kalirin, RhoGEF kinase; HAPIP, huntingtin associated protein interacting protein (duo); kalirin; ARHGEF24; DUET; duo; Hs.8004; Kalirin; serine/threonine kinase with Dbl and pleckstrin homology domains; TRAD; huntingtin-associated protein interacting protein (duo); serine/threonine kinase with Dbl- and pleckstrin homology domains; serine/threonine-protein kinase with Dbl- and pleckstrin homology domain; DUO; CHD5; CHDS5; HAPIP; FLJ12332; FLJ16443; FLJ18196; FLJ18623;
Citations
Publication ()
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